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Photometrics Prime sCMOS

Photometrics Prime sCMOS 4.2 Megapixel Cooled Scientific CMOS USB 3.0 Camera

4.2 Megapixel Cooled Scientific CMOS USB 3.0 Camera

Winner of multiple industry awards, Photometrics Prime is the first intelligent scientific CMOS (sCMOS) camera to incorporate a powerful FPGA-based Embedded Signal Processing™ engine (ESP). ESP enables advanced real-time processing features:

PrimeEnhance™ quantitatively increases the Signal to Noise Ratio by 3X-5X, increasing the clarity and quality of images.

PrimeLocate™ dynamically evaluates acquired images and reduces the surplus of data generated during high speed super-resolution imaging.

Key Features:

  • Extremely Low Read Noise
    • 1e- (median)
    • 3e- (rms)
  • Fast Frame Rates
    • 100 fps
  • Large Field of View
    • 8mm sensor diagonal
  • Optimized Pixel Size
    • 5-micron pixel pitch
  • High Quantum Efficiency
    • 72% peak QE
  • Enhanced Dynamic Range
    • 30,000:1
    • 5dB
  • ESP
    • PrimeEnhance
    • PrimeLocate
    • Multi-ROI (Region of Interest)
  • Advanced Triggering
    • Multiple Expose Out Triggering


Primary Applications:

  • Super-Resolution Microscopy
  • Light Sheet Microscopy
  • High Speed Ratiometric Imaging
  • TIRF Microscopy
  • Confocal Microscopy
Camera Specifications
Sensor TypeBAE CIS-2020F sCMOS
CCD Array2048 x 2048 pixels
Pixel Size6.5 x 6.5 µm
Sensor Dimensions13.312mm x 13.312mm (18.8mm Diagonal)
Peak Quantum Efficiency72%
Read Noise1.1e- (Median), 1.3e- (RMS)
Full Well Capacity30,000e-
Dynamic Range30,000:1
Bit Depth16-bit
Readout ModeRolling Shutter, Effective Globe Shutter
Supported Binning Modes2x2 (on FPGA)
Air Cooled-10°C @ 30°C Ambient
Dark Current 0.06e-/pixel/s
Liquid Cooled-25°C @ 30°C Ambient
Dark Current 0.01e-/pixel/s
Data InterfacePCI-Express
USB 3.0
Optical InterfaceC-mount
Mounting Points2 x 1/4 20” mounting points per side to prevent rotation
Input Trigger ModesTrigger-First – Sequence triggered on first rising edge
Edge – Each frame triggered on rising edge
SMART Streaming – Fast iteration through multiple exposure times
Output Trigger ModesFirst Row – Expose signal is high while first row is acquiring data
Any Row – Expose signal is high while any row is acquiring data
All Row – Effective Globe Shutter -Expose signal is high when all rows are acquiring data
Output Trigger SignalsExpose Out (up to four signals), Read Out, Shutter Out, Trigger Ready

Frame Rates

Array SizePCI-ExpressUSB 3.0
2048 x 204810031
1024 x 102420462
512 x 512400400
256 x 256833833